Combine strawberries, sugar and rum in a bowl and let sit for a minimum of 2 hours, preferably overnight
In a double boiler, combine ¼ cup whipping cream and white chocolate. Stir until melted and smooth.
In a large mixer bowl, beat cream cheese until creamy.
Add white chocolate mixture to cream cheese and mix until well combined
In a separate bowl (preferably with high sides) whip the remaining 1 ¼ cup whipping cream for about 1 minute using an electric mixer.
Slice the vanilla bean in half and using a knife run the edges along the vanilla bean skin to take out the vanilla. Add it to the whipping cream mixture with the powder sugar
Continue to beat for 1 more minute or until whipped and fluffy
Fold in whip cream into white chocolate cream cheese mixture.
Using a large bowl or individual serving bowls, layer pound cake, white chocolate cream and strawberries repeatedly, ending with strawberries.
Serve at once or refrigerate until ready to serve.